Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

Base Information

Chemical Name:Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester
CAS No.:160684-48-0
Molecular Formula:C₂₈H₄₇N₅O₈Si₂
Molecular Weight:637.881
Hs Code.:

Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

Synonyms:Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

Suppliers and Price of Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Hazard Codes:

MSDS Files:

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Technology Process of Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

There total 1 articles about Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38819-10-2
9-β-D-arabinofuranosylguanine

: 160684-48-0
Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) TMSCl, pyridine, 3.) NH₄OH

2: pyridine

With pyridine; ammonium hydroxide; chloro-trimethyl-silane;
DOI:10.1080/07328319708006246

Reference yield:

: 160684-48-0
Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

: 78842-13-4
2'-deoxy-2'-fluoroguanosine

Guidance literature:: Multi-step reaction with 7 steps

1: HF*pyridine

2: TsOH / dioxane

3: NaOH / pyridine; methanol

4: DMAP / CH₂Cl₂

5: TBAF / tetrahydrofuran

6: Dowex-50 / methanol

7: NH₄OH / 24 h / 55 °C

With dmap; ammonium hydroxide; sodium hydroxide; Dowex-50; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; pyridine hydrogenfluoride; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; dichloromethane;
DOI:10.1080/07328319708006246

Reference yield:

: 160684-48-0
Acetic acid (2R,3S,3aR,9aR)-2-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester

: 80681-25-0
2’-fluoro-N2-isobutyryl-2’-deoxyguanosine

Guidance literature:: Multi-step reaction with 6 steps

1: HF*pyridine

2: TsOH / dioxane

3: NaOH / pyridine; methanol

4: DMAP / CH₂Cl₂

5: TBAF / tetrahydrofuran

6: Dowex-50 / methanol

With dmap; sodium hydroxide; Dowex-50; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; pyridine hydrogenfluoride; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; dichloromethane;
DOI:10.1080/07328319708006246