methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate

Base Information

Chemical Name:methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate
CAS No.:1041204-40-3
Molecular Formula:C₃₄H₃₄N₄O₇
Molecular Weight:610.667
Hs Code.:

Synonyms:methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate

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Chemical Property of methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate

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Technology Process of methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate

There total 1 articles about methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5''-(4-oxospiro[chroman-2,4'-piperidin]-6-yl)nicotinic acid methyl ester dihydrochloride

: 1041205-10-0
[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)]benzoic acid

: 1041204-40-3
methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In water; N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 1041204-40-3
methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate

: 1041204-54-9
5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinic acid

Guidance literature:: methyl 5-{1'-[3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoyl]-4-oxospiro[chromman-2,4'-piperidin]-6-yl}nicotinate; With sodium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃;

With hydrogenchloride; In tetrahydrofuran; methanol; water; at 20 ℃;