Technology Process of (2,4-bis((2,4-dihydroxyphenoxy)methyl)phenyl)boronic acid
There total 5 articles about (2,4-bis((2,4-dihydroxyphenoxy)methyl)phenyl)boronic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
ethanol;
at 35 ℃;
for 24h;
Inert atmosphere;
DOI:10.1039/c2cc36861g
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1.5 h / 20 °C / Inert atmosphere
1.2: 3 h / 20 °C / Inert atmosphere
2.1: potassium carbonate / acetone / 24 h / 57 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
3.2: 9.5 h / -78 - 20 °C / Inert atmosphere
3.3: 14 h / Inert atmosphere
4.1: toluene-4-sulfonic acid / ethanol / 24 h / 35 °C / Inert atmosphere
With
n-butyllithium; potassium carbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; ethanol; hexane; dichloromethane; acetone;
DOI:10.1039/c2cc36861g
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: borane-THF / tetrahydrofuran / 0 - 66.5 °C / Inert atmosphere
2.1: hydrogen bromide; water; sulfuric acid / 22 h / 122 °C / Inert atmosphere
3.1: potassium carbonate / acetone / 24 h / 57 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
4.2: 9.5 h / -78 - 20 °C / Inert atmosphere
4.3: 14 h / Inert atmosphere
5.1: toluene-4-sulfonic acid / ethanol / 24 h / 35 °C / Inert atmosphere
With
n-butyllithium; borane-THF; sulfuric acid; water; hydrogen bromide; potassium carbonate; toluene-4-sulfonic acid;
In
tetrahydrofuran; ethanol; hexane; acetone;
DOI:10.1039/c2cc36861g
