methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate

Base Information

• Chemical Name: methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate
• CAS No.: 205813-64-5
• Molecular Formula: C₁₉H₂₂N₂O₃
• Molecular Weight: 326.395
• Mol file: 205813-64-5.mol

Synonyms:methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate

Chemical Property of methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate

There total 2 articles about methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1-methoxy-2-methyl-1-trimethylsiloxy-1-propene (31469-15-5) + (E)-N'-benzylidenebenzohydrazide (14850-89-6) → 2-Benzoyl-4,4-dimethyl-5-phenyl-2,4-dihydro-pyrazol-3-one + methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate (205813-64-5)

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In acetonitrile; at -20 ℃; for 6h;

DOI:10.1055/s-1998-1638

Reference yield:

1-methoxy-2-methyl-1-trimethylsiloxy-1-propene (31469-15-5) + (E)-N'-benzylidenebenzohydrazide (14850-89-6) → methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate (205813-64-5)

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In acetonitrile; at 20 ℃;

DOI:10.3987/com-99-s113

Reference yield: 99.0%

methyl 3'-N'-benzoylhydrazino-2,2-dimethyl-3-phenylpropionate (205813-64-5) → 4-phenyl-3,3-dimethyl-1-benzoylaminoazetidin-2-one (273203-43-3)

Guidance literature:

With copper(l) iodide; methyllithium; In tetrahydrofuran; diethyl ether; at 20 ℃; for 0.5h;

DOI:10.3987/com-99-s113

upstream raw materials:

1-methoxy-2-methyl-1-trimethylsiloxy-1-propene

(E)-N'-benzylidenebenzohydrazide

Downstream raw materials:

4,4-dimethyl-5-phenyl-2,4-dihydro-3H-pyrazol-3-one

4-phenyl-3,3-dimethyl-1-benzoylaminoazetidin-2-one