N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea

Base Information

• Chemical Name: N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea
• CAS No.: 125848-43-3
• Molecular Formula: C₂₃H₂₈ClN₅O₂
• Molecular Weight: 441.961

Synonyms:N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea

Chemical Property of N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea

There total 3 articles about N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

N-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>-N'-(2-nitrophenyl)urea (125848-42-2) → N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea (125848-43-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; at 25 ℃; for 2h; under 2206.5 Torr;

DOI:10.1021/jm00167a008

Reference yield:

1-(4-Aminobenzyl)-2-n-butyl-4-chloro-5-(methoxymethyl)imidazole (114772-10-0) → N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea (125848-43-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / CHCl₃ / 1.) 25 deg C, 24 h, 2.) reflux, 8 h

2: 54 percent / H₂ / 10percent Pd/C / methanol; tetrahydrofuran / 2 h / 25 °C / 2206.5 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; chloroform;

DOI:10.1021/jm00167a008

Reference yield:

2-nitrophenyl isocyanate (3320-86-3) → N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea (125848-43-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / CHCl₃ / 1.) 25 deg C, 24 h, 2.) reflux, 8 h

2: 54 percent / H₂ / 10percent Pd/C / methanol; tetrahydrofuran / 2 h / 25 °C / 2206.5 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; chloroform;

DOI:10.1021/jm00167a008

upstream raw materials:

N-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>-N'-(2-nitrophenyl)urea

1-(4-Aminobenzyl)-2-n-butyl-4-chloro-5-(methoxymethyl)imidazole

2-nitrophenyl isocyanate

Downstream raw materials:

N-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>-N'-<2-(trifluoromethanesulfonamido)phenyl>urea

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 125848-43-3 N-(2-aminophenyl)-N'-<4-<<2-butyl-4-chloro-5-(methoxymethyl)imidazol-1-yl>methyl>phenyl>urea

Send

Send

Metric Ton KG G Pound L ML

Send

Send