N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride

Base Information

• Chemical Name: N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride
• CAS No.: 1401863-33-9
• Molecular Formula: C₂₂H₂₂N₄O₂*ClH
• Molecular Weight: 410.903
• Mol file: 1401863-33-9.mol

Synonyms:N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride

Chemical Property of N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride

There total 4 articles about N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C22H22N4O2 (1401863-37-3) → N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride (1401863-33-9)

Guidance literature:

With hydrogenchloride; In ethanol; at 20 ℃; for 2h;

Reference yield:

C21H18N2O3 (952200-85-0) → N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride (1401863-33-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 20 °C

2: hydrogenchloride / ethanol / 2 h / 20 °C

With hydrogenchloride; In ethanol;

Reference yield:

D,L-5-methyltryptophan (154-06-3) → N-(2-aminoethyl)-6-methyl-1-(4-methoxyphenyl )-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride (1401863-33-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: thionyl chloride / 4 h / 0 °C / Reflux

1.2: 10 h

1.3: pH 7

2.1: sulfur / xylene / 20 h / Reflux

3.1: 20 °C

4.1: hydrogenchloride / ethanol / 2 h / 20 °C

With hydrogenchloride; thionyl chloride; sulfur; In ethanol; xylene;

upstream raw materials:

D,L-5-methyltryptophan

C₂₁H₁₈N₂O₃

C₂₂H₂₂N₄O₂