cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane

Base Information

• Chemical Name: cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane
• CAS No.: 150713-02-3
• Molecular Formula: C₁₂H₂₄O₃
• Molecular Weight: 216.321
• Mol file: 150713-02-3.mol

Synonyms:cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane

Chemical Property of cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane

There total 3 articles about cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1,3,5-Trimethyl-cyclohexane-1,3,5-tricarboxylic acid tripropyl ester (187805-78-3) → cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane (150713-02-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 20h; Heating;

DOI:10.1021/jo962145n

Reference yield: 60.0%

trimethyl-cis,cis-1,3,5-trimethyl-1,3,5-cyclohexane-tricarboxylate (79410-21-2) → cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane (150713-02-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 16h; Heating;

Reference yield:

Kemp's triacid (79410-20-1) → cis,cis-1,3,5-tris(hydroxymethyl)-1,3,5-trimethylcyclohexane (150713-02-3)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / 1 h / Heating

2: 81 percent / LiAlH₄ / tetrahydrofuran / 20 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1021/jo962145n

upstream raw materials:

trimethyl-cis,cis-1,3,5-trimethyl-1,3,5-cyclohexane-tricarboxylate

1,3,5-Trimethyl-cyclohexane-1,3,5-tricarboxylic acid tripropyl ester

Kemp's triacid

Downstream raw materials:

5-formyl-cis,cis-1,3,5-trimethyl-3-(hydroxymethyl)cyclohexane-1-carboxylic acid lactone

cis,cis-1,3,5-triformyl-1,3,5-trimethylcyclohexane

cis,cis-1,3,5-tris<(diphenylphosphanyl)methyl>-1,3,5-trimethylcyclohexane

cis,cis-1,3,5-trimethyl-1,3,5-tris<(trifluoromethylsulfonyloxy)methyl>cyclohexane