N⁽¹⁾-(p-aminobenzoyl)-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane

Base Information

• Chemical Name: N⁽¹⁾-(p-aminobenzoyl)-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane
• CAS No.: 1297523-37-5
• Molecular Formula: C₃₂H₅₅N₅O₇
• Molecular Weight: 621.818

Synonyms:N⁽¹⁾-(p-aminobenzoyl)-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane

Chemical Property of N⁽¹⁾-(p-aminobenzoyl)-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁽¹⁾-(p-aminobenzoyl)-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane

There total 8 articles about N⁽¹⁾-(p-aminobenzoyl)-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N(1)-p-nitrobenzoyl-N(4),N(9),N(12)-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane (1297523-34-2) → N(1)-(p-aminobenzoyl)-N(4),N(9),N(12)-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane (1297523-37-5)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 8h;

DOI:10.1039/c0jm04064a

Reference yield:

3-(4-[(2-cyanoethyl)amino]butylamino)propanenitrile (14209-32-6) → N(1)-(p-aminobenzoyl)-N(4),N(9),N(12)-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane (1297523-37-5)

Guidance literature:

Multi-step reaction with 7 steps

1: triethylamine / methanol / 24 h / 0 - 20 °C

2: palladium on activated charcoal; lithium hydroxide monohydrate; hydrogen / 1,4-dioxane; water / 20 °C

3: methanol / -78 - 0 °C / Inert atmosphere

4: methanol / 16 h / 0 - 20 °C / Inert atmosphere

5: water; potassium carbonate / 3 h / Reflux

6: triethylamine / toluene / 8 h / 60 °C

7: palladium on activated charcoal; hydrogen / methanol / 8 h / 20 °C

With lithium hydroxide monohydrate; palladium on activated charcoal; water; hydrogen; potassium carbonate; triethylamine; In 1,4-dioxane; methanol; water; toluene;

DOI:10.1039/c0jm04064a

Reference yield:

1-trifluoroacetyl-5,10,14-tris-Boc-spermine (201984-66-9) → N(1)-(p-aminobenzoyl)-N(4),N(9),N(12)-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane (1297523-37-5)

Guidance literature:

Multi-step reaction with 3 steps

1: water; potassium carbonate / 3 h / Reflux

2: triethylamine / toluene / 8 h / 60 °C

3: palladium on activated charcoal; hydrogen / methanol / 8 h / 20 °C

With palladium on activated charcoal; water; hydrogen; potassium carbonate; triethylamine; In methanol; toluene;

DOI:10.1039/c0jm04064a

upstream raw materials:

N⁽¹⁾-p-nitrobenzoyl-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane

3-(4-[(2-cyanoethyl)amino]butylamino)propanenitrile

tri-Boc-spermine

4-nitro-benzoyl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1297523-37-5 N⁽¹⁾-(p-aminobenzoyl)-N⁽⁴⁾,N⁽⁹⁾,N⁽¹²⁾-tri-(tert-butyloxycarbonyl)-1,12-diamino-4,9-diazadodecane

Send

Send

Metric Ton KG G Pound L ML

Send

Send