C₃₃H₄₄O₇Si

Base Information

• Chemical Name: C₃₃H₄₄O₇Si
• CAS No.: 219780-80-0
• Molecular Formula: C₃₃H₄₄O₇Si
• Molecular Weight: 580.794
• Mol file: 219780-80-0.mol

Synonyms:C₃₃H₄₄O₇Si

Chemical Property of C₃₃H₄₄O₇Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₄₄O₇Si

There total 16 articles about C₃₃H₄₄O₇Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

benzaldehyde dimethyl acetal (1125-88-8) + C26H40O7Si (219780-79-7) → C33H44O7Si (219780-80-0)

Guidance literature:

With pyridinium p-toluenesulfonate; In benzene; Heating;

DOI:10.1021/ja9824932

Reference yield:

C39H62O6Si2 (219780-47-9) → C33H44O7Si (219780-80-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 66 percent / diethyl zinc / toluene; hexane / 0.5 h / 0 °C

2: 77 percent / Dess-Martin periodinane / CH₂Cl₂ / 12 h / 20 °C

3: 84 percent / H₂ / Pd(OH)2 / ethanol / 0.5 h / 20 °C

4: pyridine / CH₂Cl₂ / 2 h / -45 °C

5: 0.742 g / TBAF; AcOH / tetrahydrofuran / 2.5 h / 20 °C

6: 86 percent / pyridinium p-toluenesulfonate / benzene / 1 h / Heating

With pyridine; tetrabutyl ammonium fluoride; hydrogen; diethylzinc; pyridinium p-toluenesulfonate; Dess-Martin periodane; acetic acid; palladium dihydroxide; In tetrahydrofuran; ethanol; hexane; dichloromethane; toluene; benzene; 1: Cycloaddition / 2: Dess-Martin oxidation / 3: Hydrogenolysis / 4: cyclocondensation / 5: desilylation / 6: cyclocondensation;

DOI:10.1021/ja9939439

Reference yield:

C40H62O6Si2 (219780-48-0) → C33H44O7Si (219780-80-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 84 percent / H₂ / Pd(OH)2 / ethanol / 0.5 h / 20 °C

2: pyridine / CH₂Cl₂ / 2 h / -45 °C

3: 0.742 g / TBAF; AcOH / tetrahydrofuran / 2.5 h / 20 °C

4: 86 percent / pyridinium p-toluenesulfonate / benzene / 1 h / Heating

With pyridine; tetrabutyl ammonium fluoride; hydrogen; pyridinium p-toluenesulfonate; acetic acid; palladium dihydroxide; In tetrahydrofuran; ethanol; dichloromethane; benzene; 1: Hydrogenolysis / 2: cyclocondensation / 3: desilylation / 4: cyclocondensation;

DOI:10.1021/ja9939439

upstream raw materials:

benzaldehyde dimethyl acetal

C₂₆H₄₀O₇Si

C₃₃H₅₈O₆Si₂

C₃₄H₅₆O₇Si₂

Downstream raw materials:

7-(2,2,2-trichloroethyloxycarbonyl)baccatin III

taxol

C₂₆H₃₄O₆

C₂₆H₃₄O₆