(6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester

Base Information

• Chemical Name: (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester
• CAS No.: 82895-21-4
• Molecular Formula: C₂₃H₂₁ClN₂O₄S
• Molecular Weight: 456.95

Synonyms:(6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester

Chemical Property of (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester

There total 13 articles about (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-Chloromethyl-2-[2-(4-nitro-benzenesulfonylsulfanyl)-4-oxo-3-phenylacetylamino-azetidin-1-yl]-but-3-enoic acid benzyl ester (95463-15-3) → 3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester (82895-21-4,84985-48-8)

Guidance literature:

With ammonia; In N,N-dimethyl-formamide; at -30 - -20 ℃; for 1h;

DOI:10.1016/S0040-4039(00)87295-0

Reference yield: 86.0%

(R)-3-Chloromethyl-2-[(2R,3R)-2-(4-nitro-benzenesulfonylsulfanyl)-4-oxo-3-phenylacetylamino-azetidin-1-yl]-but-3-enoic acid benzyl ester (82895-17-8) → (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester (82895-21-4)

Guidance literature:

With ammonia; In N,N-dimethyl-formamide; at -30 - -20 ℃; for 1h;

DOI:10.1002/bscb.19820911202

Reference yield: 78.0%

2-(2-Benzenesulfonylsulfanyl-4-oxo-3-phenylacetylamino-azetidin-1-yl)-3-chloromethyl-but-3-enoic acid benzyl ester (95406-21-6) → 3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester (82895-21-4,84985-48-8)

Guidance literature:

With ammonia; In N,N-dimethyl-formamide; at -30 - -20 ℃; for 1h;

DOI:10.1016/S0040-4039(00)87295-0

upstream raw materials:

2-(2-Benzenesulfonylsulfanyl-4-oxo-3-phenylacetylamino-azetidin-1-yl)-3-chloromethyl-but-3-enoic acid benzyl ester

3-Chloromethyl-2-[2-(4-nitro-benzenesulfonylsulfanyl)-4-oxo-3-phenylacetylamino-azetidin-1-yl]-but-3-enoic acid benzyl ester

2-(2-Benzenesulfonylsulfanyl-4-oxo-3-phenylacetylamino-azetidin-1-yl)-3-methyl-but-3-enoic acid benzyl ester

benzyl 2-[3-phenylacetamido-4-(p-nitrobenzenesulfonylthio)-2-azetidinon-1-yl]-3-methyl-3-butenoate

Downstream raw materials:

(6R)-3-methyl-8-oxo-7t-(2-phenyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester

(6R,7R)-3-(5-Methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 82895-21-4 (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send