(-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

Base Information

Chemical Name:(-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate
CAS No.:128503-27-5
Molecular Formula:C₁₃H₁₀Cl₂O₅
Molecular Weight:317.125
Hs Code.:

Synonyms:(-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

Suppliers and Price of (-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

There total 5 articles about (-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 128503-26-4
(1S,2S,3S,4S,5S)-5-endo-chloro-3-exo-hydroxy-3-endo-<(tert-butyl)dimethylsilyloxy>-7-oxabicyclo<2.2.1>hept-2-exo-yl metachlorobenzoate

: 128503-27-5
(-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 66h;
DOI:10.1016/S0040-4039(00)70712-X

Reference yield:

: 128503-25-3
(+)-(1S,2S,3R,4S)-5-chloro-3-exo-hydroxy-3-endo-<(tert-butyl)dimethylsilyloxy>-7-oxabicyclo<2.2.1>hept-5-en-2-exo-yl metachlorobenzoate

: 128503-27-5
(-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

Guidance literature:: With hydrogen; sodium hydrogencarbonate; sodium carbonate; 3-chloro-benzenecarboperoxoic acid; Yield given. Multistep reaction; 1) ethyl acetate, a) 1 atm, 15 h, b) 1 atm, 20 deg C, 24 h, 2) 20 deg C, 66 h;
DOI:10.1016/S0040-4020(01)88357-5

Reference yield:

: 88708-22-9
(+)-(1R,4R)-7-oxabicyclo<2.2.1>-hept-5-en-2-one

: 128503-27-5
(-)-(1S,4S,5S,7S)-7-endo-chloro-3-oxo-2,8-dioxabicyclo<3.2.1>oct-4-exo-yl metachlorobenzoate

Guidance literature:: Multi-step reaction with 4 steps

2: 95 percent / Et₃N / dimethylformamide / 40 °C

3: 69 percent / AcONa / CH₂Cl₂ / a) 0 deg C, 5 min., b) 20 deg C, 30 min.

4: 1) Na₂CO₃, H₂, 2) NaHCO₃, mCPBA / 1) ethyl acetate, a) 1 atm, 15 h, b) 1 atm, 20 deg C, 24 h, 2) 20 deg C, 66 h

With hydrogen; sodium acetate; sodium hydrogencarbonate; sodium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)88357-5