N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester

Base Information

• Chemical Name: N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester
• CAS No.: 110850-88-9
• Molecular Formula: C₂₅H₃₉N₃O₈
• Molecular Weight: 512.577
• Mol file: 110850-88-9.mol

Synonyms:N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester

Chemical Property of N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester

There total 1 articles about N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(tert-butyloxycarbonyl)-γ-succinimidyl-<α-2H>glutamic acid methyl ester (110850-73-2) + N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol, hydrochloride salt (110874-15-2) → N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester (110850-88-9)

Guidance literature:

With N'-ethyl-N,N-dimethyl-hydrazine; triethylamine; Yield given. Multistep reaction; 1.) DMF, 24 h, 2.) DMF, 1 h;

DOI:10.1021/jo00233a007

Reference yield:

N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol-N'-(tert-butyloxycarbonyl)<α-2H>glutamic acid methyl ester (110850-88-9) → C25H35(2)H2N2(15)NO9 (110850-89-0)

Guidance literature:

With dipyridinium dichromate; In N,N-dimethyl-formamide; at 50 ℃; for 24h;

DOI:10.1021/jo00233a007

upstream raw materials:

N-(tert-butyloxycarbonyl)-γ-succinimidyl-<α-2H>glutamic acid methyl ester

N-(benzyloxycarbonyl)-<ε-15N,α-2H>lysinol, hydrochloride salt

Downstream raw materials:

C₂₅H₃₅⁽²⁾H₂N₂⁽¹⁵⁾NO₉