C₄₁H₇₀N₆O₈SSi

Base Information

• Chemical Name: C₄₁H₇₀N₆O₈SSi
• CAS No.: 1026564-54-4
• Molecular Formula: C₄₁H₇₀N₆O₈SSi
• Molecular Weight: 835.194
• Mol file: 1026564-54-4.mol

Synonyms:C₄₁H₇₀N₆O₈SSi

Chemical Property of C₄₁H₇₀N₆O₈SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₁H₇₀N₆O₈SSi

There total 14 articles about C₄₁H₇₀N₆O₈SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-{[1-(2,5-dimethyloxazol-4-yl)ethyl]carbamoyl}-5-(N-methylmethan-5-ylsulfonamido)benzoic acid (940879-56-1) + C24H51N3O3Si (1027369-55-6) → C41H70N6O8SSi (1026564-54-4)

Guidance literature:

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 44h;

DOI:10.1021/jm061338s

Reference yield:

1-(2,5-dimethyloxazol-4-yl)ethanol (940879-48-1) → C41H70N6O8SSi (1026564-54-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 159 mg / diphenyl phosphoryl azide; DBU / toluene / 17 h / 23 °C

2.1: PPh₃ / tetrahydrofuran / 7 h / 23 °C

2.2: 57.5 mg / H₂O / tetrahydrofuran / 12 h / 55 °C

3.1: EDC; HOBT; diisopropylethylamine / dimethylformamide; CH₂Cl₂ / 20 h / 20 °C

4.1: 63 mg / aq. NaOH / tetrahydrofuran; methanol

5.1: diisopropylethylamine; HOBT; EDC / CH₂Cl₂; dimethylformamide / 44 h / 20 °C

With sodium hydroxide; diphenyl phosphoryl azide; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/jm061338s

Reference yield:

C7H10N4O (940879-49-2) → C41H70N6O8SSi (1026564-54-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: PPh₃ / tetrahydrofuran / 7 h / 23 °C

1.2: 57.5 mg / H₂O / tetrahydrofuran / 12 h / 55 °C

2.1: EDC; HOBT; diisopropylethylamine / dimethylformamide; CH₂Cl₂ / 20 h / 20 °C

3.1: 63 mg / aq. NaOH / tetrahydrofuran; methanol

4.1: diisopropylethylamine; HOBT; EDC / CH₂Cl₂; dimethylformamide / 44 h / 20 °C

With sodium hydroxide; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm061338s

upstream raw materials:

3-{[1-(2,5-dimethyloxazol-4-yl)ethyl]carbamoyl}-5-(N-methylmethan-5-ylsulfonamido)benzoic acid

C₂₄H₅₁N₃O₃Si

1-(2,5-dimethyloxazol-4-yl)ethanol

C₇H₁₀N₄O

Refernces