3-Amino-4-hydroxybenzenesulfonamide

Base Information

• Chemical Name: 3-Amino-4-hydroxybenzenesulfonamide
• CAS No.: 98-32-8
• Molecular Formula: C6H8N2O3S
• Molecular Weight: 188.207
• Hs Code.: 2935009090
• European Community (EC) Number: 202-657-0
• NSC Number: 4976
• UNII: S18Z30538J
• DSSTox Substance ID: DTXSID0059166
• Nikkaji Number: J124.128A
• Wikidata: Q27288439
• Pharos Ligand ID: CKDTM47TLYUT
• ChEMBL ID: CHEMBL4289589
• Mol file: 98-32-8.mol

Synonyms:4-hydroxy-3-aminobenzenesulfonamide;4-hydroxymetanilamide

Chemical Property of 3-Amino-4-hydroxybenzenesulfonamide

Chemical Property:

• Melting Point: 199-201 °C
• Boiling Point: 454.5 °C at 760 mmHg
• PKA: 7?+-.0.20(Predicted)
• Flash Point: 228.7 °C
• PSA: 114.79000
• Density: 1.58 g/cm³
• LogP: 1.98410
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: soluble in Methanol
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 188.02556330
• Heavy Atom Count: 12
• Complexity: 246

Purity/Quality:

99% ^*data from raw suppliers

2-Aminophenol-4-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1S(=O)(=O)N)N)O

Technology Process of 3-Amino-4-hydroxybenzenesulfonamide

There total 4 articles about 3-Amino-4-hydroxybenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ C48H97N3O2 (93858-16-3)

Guidance literature:

Reference yield:

4-hydroxy-3-nitrobenzenesulfonamide (24855-58-1) → 3-amino-4-hydroxybenzenesulfonamide (98-32-8)

Guidance literature:

With hydrogenchloride; zinc; In ethanol; Heating;

Reference yield:

→ 3-amino-4-hydroxybenzenesulfonamide (98-32-8)

Guidance literature:

With sodium hydroxide; sodium dithionite;

DOI:10.1039/jr9390000608

upstream raw materials:

4-hydroxy-3-nitrobenzenesulfonamide

Downstream raw materials:

3-amino-4-hydroxy-5-nitro-benzenesulfonamide

(2-Hydroxy-5-sulfamoyl-phenylazo)-2-methoxy-acetoacetanilid

(2-Hydroxy-5-sulfamoyl-phenylazo)-4-methyl-acetoacetanilid

(2-Hydroxy-5-sulfamoyl-phenylazo)-4-chlor-acetoacetanilid

Refernces