Technology Process of 5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)oxymethyl-2'-deoxyuridine
There total 7 articles about 5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)oxymethyl-2'-deoxyuridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride; pyridine hydrochloride;
In
tetrahydrofuran;
for 0.5h;
DOI:10.1002/recl.19941130607
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 84 percent / CF3COOH / Heating
2: 90 percent / pyridine / 0.5 h
3: 65 percent / K2CO3 / methanol
4: 50 percent / HgBr2; Hg(CN)2; powdered molecular sieves, 4 Angstroem / acetonitrile / 3 h
5: 78 percent / Et3N*3HF / pyridine / 16 h
With
molecular sieve; 4 A molecular sieve; mercury(II) cyanide; potassium carbonate; triethylamine tris(hydrogen fluoride); trifluoroacetic acid; mercury dibromide;
In
pyridine; methanol; acetonitrile;
1: Acetylation / 2: silylation, bifunctional / 3: Deacetylation / 4: Condensation / 5: desilylation;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 90 percent / pyridine / 0.5 h
2: 65 percent / K2CO3 / methanol
3: 50 percent / HgBr2; Hg(CN)2; powdered molecular sieves, 4 Angstroem / acetonitrile / 3 h
4: 78 percent / Et3N*3HF / pyridine / 16 h
With
molecular sieve; 4 A molecular sieve; mercury(II) cyanide; potassium carbonate; triethylamine tris(hydrogen fluoride); mercury dibromide;
In
pyridine; methanol; acetonitrile;
1: silylation, bifunctional / 2: Deacetylation / 3: Condensation / 4: desilylation;
