Technology Process of C18H22O5
There total 7 articles about C18H22O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
AD-mix-β; water;
In
tert-butyl alcohol;
at 20 ℃;
for 3h;
optical yield given as %ee;
Inert atmosphere;
DOI:10.1016/j.tet.2011.04.094
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 0 °C / Inert atmosphere
2.1: potassium tert-butylate / tetrahydrofuran / 2.08 h / -78 - 0 °C / Inert atmosphere
2.2: 16.08 h / 20 °C / Inert atmosphere
3.1: AD-mix-β; water / tert-butyl alcohol / 3 h / 20 °C / Inert atmosphere
With
AD-mix-β; potassium tert-butylate; water; potassium carbonate;
In
tetrahydrofuran; N,N-dimethyl-formamide; tert-butyl alcohol;
3.1: Sharpless dihydroxylation;
DOI:10.1016/j.tet.2011.04.094
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogenchloride / ethanol; water / Inert atmosphere
2.1: triethylamine; magnesium chloride / acetonitrile / 0.5 h / Inert atmosphere; Reflux
3.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 0 °C / Inert atmosphere
4.1: potassium tert-butylate / tetrahydrofuran / 2.08 h / -78 - 0 °C / Inert atmosphere
4.2: 16.08 h / 20 °C / Inert atmosphere
5.1: AD-mix-β; water / tert-butyl alcohol / 3 h / 20 °C / Inert atmosphere
With
hydrogenchloride; AD-mix-β; potassium tert-butylate; water; potassium carbonate; triethylamine; magnesium chloride;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;
2.1: Casiraghi/Hoflokken ortho-formylation / 5.1: Sharpless dihydroxylation;
DOI:10.1016/j.tet.2011.04.094
