5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline

Base Information

• Chemical Name: 5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline
• CAS No.: 1148021-50-4
• Molecular Formula: C₂₁H₁₅BrN₄O₅
• Molecular Weight: 483.278
• Mol file: 1148021-50-4.mol

Synonyms:5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline

Chemical Property of 5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline

There total 1 articles about 5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-bromo-2,6-dimethyl-phenol (2374-05-2) + 5-chloro-N1-(4'-cyanophenyl)-2,4-dinitroaniline (1148021-73-1) → 5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline (1148021-50-4)

Guidance literature:

4-bromo-2,6-dimethyl-phenol; 5-chloro-N₁-(4'-cyanophenyl)-2,4-dinitroaniline; With potassium carbonate; In dimethyl sulfoxide; at 192 ℃; for 0.25h; Microwave irradiation;

With hydrogenchloride; In water; dimethyl sulfoxide; for 0.5h; Cooling with ice;

Reference yield: 95.0%

5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline (1148021-50-4) → 5-(4''-bromo-2'',6''-dimethylphenoxy)-N1-(4'-cyanophenyl)benzene-1,2,4-triamine (1148021-58-2)

Guidance literature:

With iron(III) chloride hexahydrate; pyrographite; hydrazine hydrate; In isopropyl alcohol; Reflux;

DOI:10.1021/jm1002952

Reference yield: 85.0%

5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline (1148021-50-4) → 5-(4''-bromo-2'',6''-dimethylphenoxy)-N1-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine (1148021-54-8)

Guidance literature:

With formic acid; palladium 10% on activated carbon; triethylamine; In acetonitrile; at -15 ℃; chemoselective reaction; Reflux;

DOI:10.1021/jm1002952

upstream raw materials:

4-bromo-2,6-dimethyl-phenol

5-chloro-N₁-(4'-cyanophenyl)-2,4-dinitroaniline

Downstream raw materials:

N-(4'-cyanophenyl)-5-(4'-propenylcyano-2',6'-dimethylphenoxy)-2,4-dinitroaniline

5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine

5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)benzene-1,2,4-triamine