tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate

Base Information

Chemical Name:tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate
CAS No.:1138034-96-4
Molecular Formula:C₂₄H₂₆FNO₅S₂
Molecular Weight:491.605
Hs Code.:

Synonyms:tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate

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Technology Process of tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate

There total 1 articles about tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1138034-94-2
tert-butyl {[4-(2-fluoro-3-formylphenyl)-5-(phenylsulfonyl)thiophen-2-yl]methyl}methylcarbamate

: 1138034-96-4
tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate

Guidance literature:: With methanol; sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield:

: 1138034-96-4
tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate

: 1138041-34-5
(2-fluoro-3-{5-[(methylamino)methyl]-2-(phenylsulfonyl)thiophen-3-yl}phenyl)methanol

Guidance literature:: tert-butyl ({4-[2-fluoro-3-(hydroxymethyl)phenyl]-5-(phenylsulfonyl)thiophen-2-yl}methyl)methylcarbamate; With hydrogenchloride; In ethanol; ethyl acetate; at 20 ℃; for 4h;

With sodium hydrogencarbonate; In water;