2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline

Base Information

• Chemical Name: 2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline
• CAS No.: 1087319-47-8
• Molecular Formula: C₂₆H₂₇NO₂
• Molecular Weight: 385.506

Synonyms:2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline

Chemical Property of 2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline

Chemical Property:

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Technology Process of 2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline

There total 1 articles about 2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline-2-carbonitrile → 2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline (1087319-47-8)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 15h; Reflux;

DOI:10.1002/ejoc.200800512

Reference yield: 95.0%

2-[2-(1,3-benzodioxol-5-yl)ethyl]-1-(1-phenylethyl)-1,2,3,4-tetrahydroquinoline (1087319-47-8) → 2-(2-(benzo[d][1,3]-dioxol-5-yl)ethyl)-1,2,3,4-tetrahydroquinoline (375395-24-7,608525-33-3)

Guidance literature:

With palladium hydroxide on carbon; hydrogen; In methanol; ethyl acetate; at 20 ℃; for 48h; under 1520.1 Torr;

DOI:10.1002/ejoc.200800512

Downstream raw materials:

2-(2-(benzo[d][1,3]-dioxol-5-yl)ethyl)-1,2,3,4-tetrahydroquinoline

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