C₂₃H₃₂SO₄C₅H₁₀O

Base Information

• Chemical Name: C₂₃H₃₂SO₄C₅H₁₀O
• CAS No.: 793685-17-3
• Molecular Formula: C₂₈H₄₂O₅S
• Molecular Weight: 490.704
• Mol file: 793685-17-3.mol

Synonyms:C₂₃H₃₂SO₄C₅H₁₀O

Chemical Property of C₂₃H₃₂SO₄C₅H₁₀O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₂SO₄C₅H₁₀O

There total 17 articles about C₂₃H₃₂SO₄C₅H₁₀O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

phenylcarbonochloridothioate (1005-56-7) + C21H38O4 (793685-16-2) → C23H32SO4C5H10O (793685-17-3)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.tet.2004.06.143

Reference yield:

methyl (3R)-3-hydroxypentanoate (42558-50-9,56009-31-5,60793-22-8,133098-13-2) → C23H32SO4C5H10O (793685-17-3)

Guidance literature:

Multi-step reaction with 16 steps

1.1: TsOH / CH₂Cl₂ / 20 °C

2.1: LiAlH₄ / tetrahydrofuran

3.1: NaH / tetrahydrofuran / Heating

4.1: TsOH / methanol / 20 °C

5.1: TsOH; MeOH

5.2: DEAD; PPh₃

6.1: aq. KOH / ethanol

7.1: NaH

8.1: H₂ / Pd/C / methanol

9.1: 96 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 20 °C

10.1: 95 percent / Et₃N; DMAP

11.1: 60 percent / NaH; Pd(PPh₃)4 / tetrahydrofuran / 4 h / 70 °C

12.1: 87 percent / H₂ / Pd/C / ethyl acetate / 15 h / atmospheric pressure

13.1: DABCO / o-xylene; H₂O / 16 h / Heating

13.2: 62 percent / NaOMe / methanol; tetrahydrofuran / 17 h / 20 °C

14.1: 99 percent / lIaLh₄ / tetrahydrofuran / 0 - 20 °C

15.1: 94 percent / pyridine / CH₂Cl₂ / 0 - 20 °C

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; methanol; dmap; potassium hydroxide; lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; oxalyl dichloride; hydrogen; sodium hydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; o-xylene; water; ethyl acetate; 5.2: Mitsunobu reaction / 9.1: Swern oxidation / 12.1: Trost-Tsuji reaction / 14.1: Taber's decarbomethoxylation;

DOI:10.1016/j.tet.2004.06.143

Reference yield:

C15H24O5 (116949-06-5) → C23H32SO4C5H10O (793685-17-3)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 87 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 20 °C

2.1: 60 percent / NaH; Pd(PPh₃)4 / tetrahydrofuran / 4 h / 70 °C

3.1: 87 percent / H₂ / Pd/C / ethyl acetate / 15 h / atmospheric pressure

4.1: DABCO / o-xylene; H₂O / 16 h / Heating

4.2: 62 percent / NaOMe / methanol; tetrahydrofuran / 17 h / 20 °C

5.1: 99 percent / lIaLh₄ / tetrahydrofuran / 0 - 20 °C

6.1: 94 percent / pyridine / CH₂Cl₂ / 0 - 20 °C

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; oxalyl dichloride; hydrogen; sodium hydride; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; o-xylene; water; ethyl acetate; 1.1: Swern oxidation / 2.1: Trost-Tsuji reaction / 4.1: Taber's decarbomethoxylation;

DOI:10.1016/j.tet.2004.06.143

upstream raw materials:

phenylcarbonochloridothioate

C₂₁H₃₈O₄

methyl (3R)-3-hydroxypentanoate

(R)-1,3-pentanediol 3-(2-tetrahydropyranyl) ether

Downstream raw materials:

cyoctol