1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide

Base Information

• Chemical Name: 1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide
• CAS No.: 1067324-34-8
• Molecular Formula: C₂₂H₁₇O₂P
• Molecular Weight: 344.35
• Mol file: 1067324-34-8.mol

Synonyms:1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide

Chemical Property of 1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide

There total 1 articles about 1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

4-(3-hydroxy-1-propyn-1-yl)-benzaldehyde (80151-10-6) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide (1067324-34-8)

Guidance literature:

With triethylamine; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1021/jo8013462

Reference yield: 57.0%

1-(p-formylphenyl)propa-1,2-dien-1-yl diphenyl phosphine oxide (1067324-34-8) → 1-(4-formylphenyl)-3-hydroxy-2-iodoprop-1(E)-enyl diphenyl phosphine oxide (1067324-77-9)

Guidance literature:

With water; iodine; silver nitrate; In acetonitrile; at 20 ℃; for 61h;

DOI:10.1021/jo8013462

upstream raw materials:

4-(3-hydroxy-1-propyn-1-yl)-benzaldehyde

chloro-diphenylphosphine

Downstream raw materials:

1-(4-formylphenyl)-3-hydroxy-2-iodoprop-1(E)-enyl diphenyl phosphine oxide