methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

Base Information

Chemical Name:methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride
CAS No.:106807-01-6
Molecular Formula:C₁₉H₂₁NO₄*ClH
Molecular Weight:363.841
Hs Code.:

Synonyms:methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

Suppliers and Price of methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

There total 6 articles about methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 106787-80-8
methyl 6,7-dihydroxy-1-(2-phenyl)ethyl-3,4-dihydroisoquinoline-3-carboxylate hydrobromide

: 106807-01-6
methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

Guidance literature:: With hydrogenchloride; sodium tetrahydroborate; In methanol; at -78 ℃; for 1h;
DOI:10.1248/cpb.34.1994

Reference yield:

: 15781-96-1
3-phenylpropionic anhydride

: 106807-01-6
methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / 20 h / Ambient temperature

2: Lawesson's reagent / 1,2-dimethoxy-ethane / 24 h / Ambient temperature

3: 10 percent anhydrous HCl / methanol / 1 h / Ambient temperature

4: 57 percent / 4-nitrobenzyl bromide / acetonitrile / 72 h / Heating

5: 63 percent / 1.) NaBH₄, 2.) HCl / methanol / 1 h / -78 °C

With Lawessons reagent; pyridine; hydrogenchloride; sodium tetrahydroborate; 1-bromomethyl-4-nitro-benzene; In methanol; 1,2-dimethoxyethane; acetonitrile;
DOI:10.1248/cpb.34.1994

Reference yield:

: 40611-00-5
DL-3-(3,4-dihydroxyphenyl)alanine methyl ester hydrochloride

: 106807-01-6
methyl cis-6,7-dihydro-1-(2-phenyl)ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / 20 h / Ambient temperature

2: Lawesson's reagent / 1,2-dimethoxy-ethane / 24 h / Ambient temperature

3: 10 percent anhydrous HCl / methanol / 1 h / Ambient temperature

4: 57 percent / 4-nitrobenzyl bromide / acetonitrile / 72 h / Heating

5: 63 percent / 1.) NaBH₄, 2.) HCl / methanol / 1 h / -78 °C

With Lawessons reagent; pyridine; hydrogenchloride; sodium tetrahydroborate; 1-bromomethyl-4-nitro-benzene; In methanol; 1,2-dimethoxyethane; acetonitrile;
DOI:10.1248/cpb.34.1994