{4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde

Base Information

• Chemical Name: {4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde
• CAS No.: 681850-73-7
• Molecular Formula: C₁₆H₂₂O₂Si
• Molecular Weight: 274.435
• Mol file: 681850-73-7.mol

Synonyms:{4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde

Chemical Property of {4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde

There total 1 articles about {4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

iodobenzene (591-50-4) + (Z)-4-(3-Trimethylsilanyl-prop-2-ynyloxy)-but-2-en-1-ol → {4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde (681850-73-7)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; triethylamine; for 3h; Heating;

DOI:10.1002/anie.200461134

Reference yield:

1-methyl-piperazine (109-01-3) + {4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde (681850-73-7) → 1-Methyl-4-(2-{4-[1-phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-ethyl)-piperazine

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; formic acid; triethylamine; In 1,2-dichloro-ethane; at 60 ℃; for 12h;

DOI:10.1002/anie.200461134

Reference yield:

morpholine (110-91-8,99108-56-2) + {4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-acetaldehyde (681850-73-7) → 4-(2-{4-[1-Phenyl-1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-furan-3-yl}-ethyl)-morpholine

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; formic acid; triethylamine; In 1,2-dichloro-ethane; at 60 ℃; for 12h;

DOI:10.1002/anie.200461134

upstream raw materials:

iodobenzene