C₂₀H₁₆F₃NO₃

Base Information

Chemical Name:C₂₀H₁₆F₃NO₃
CAS No.:1565778-55-3
Molecular Formula:C₂₀H₁₆F₃NO₃
Molecular Weight:375.347
Hs Code.:

C<sub>20</sub>H<sub>16</sub>F<sub>3</sub>NO<sub>3</sub>

Synonyms:C₂₀H₁₆F₃NO₃

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Chemical Property of C₂₀H₁₆F₃NO₃

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Technology Process of C₂₀H₁₆F₃NO₃

There total 5 articles about C₂₀H₁₆F₃NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1565778-54-2
C₁₈H₁₃BrF₃NO₂

: 97674-02-7
tributyl(1-ethoxyvinyl)stannane

: 1565778-55-3
C₂₀H₁₆F₃NO₃

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 119 ℃;

Reference yield:

: 39755-95-8
5-methoxyisatine

: 1565778-55-3
C₂₀H₁₆F₃NO₃

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium hydroxide / water / 80 °C

1.2: 120 h / 20 °C

2.1: N-Bromosuccinimide / tetrahydrofuran / 2.5 h / 20 °C

3.1: caesium carbonate / N,N-dimethyl-formamide / 2 h / Inert atmosphere

4.1: copper(l) iodide / N,N-dimethyl-formamide / 0.5 h / 100 °C / Microwave irradiation

5.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 119 °C

With N-Bromosuccinimide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; potassium hydroxide; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide;

Reference yield:

: 857758-51-1
3-hydroxy-6-methoxy-quinoline-4-carboxylic acid

: 1565778-55-3
C₂₀H₁₆F₃NO₃

Guidance literature:: Multi-step reaction with 4 steps

1: N-Bromosuccinimide / tetrahydrofuran / 2.5 h / 20 °C

2: caesium carbonate / N,N-dimethyl-formamide / 2 h / Inert atmosphere

3: copper(l) iodide / N,N-dimethyl-formamide / 0.5 h / 100 °C / Microwave irradiation

4: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 119 °C

With N-Bromosuccinimide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;