methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Base Information

Chemical Name:methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside
CAS No.:122672-72-4
Molecular Formula:C₃₀H₄₉NO₆Si
Molecular Weight:547.808
Hs Code.:

methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Synonyms:methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Suppliers and Price of methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

There total 11 articles about methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 18871-66-4
N,N-dimethylacetamide dimethyl acetal

: 122672-71-3
(10R)-methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-((Z)-2-hydroxypropylidene)-2-C-methyl-α-D-ribo-hexopyranoside

: 122672-72-4
methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Guidance literature:: With 4 A molecular sieve; In toluene; Heating;
DOI:10.1021/jo00283a034

Reference yield:

: 122592-17-0
methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2-deoxy-2-C-methyl-3-C-vinyl-α-D-allopyranoside

: 122672-72-4
methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1: 69 percent / SOCl₂, pyridine / tetrahydrofuran / 1 h / 0 °C

2: dimethylformamide / 2 h / 100 °C

3: NaOMe / methanol / Ambient temperature

4: PCC, AcONa, Celite / CH₂Cl₂ / 0.33 h / Ambient temperature

5: tetrahydrofuran / 0.17 h

6: Ph₃P, diethyl azodicarboxylate / tetrahydrofuran / 0.08 h / Ambient temperature

7: MeLi / diethyl ether; tetrahydrofuran / 0.17 h / 0 °C

8: 70 percent / molecular sieves 4A / toluene / Heating

With pyridine; thionyl chloride; 4 A molecular sieve; Celite; methyllithium; sodium methylate; sodium acetate; triphenylphosphine; pyridinium chlorochromate; diethylazodicarboxylate; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00283a034

Reference yield:

: 122622-39-3
(2R,4aR,6S,7R,8S,8aR)-7-(2-Hydroxy-ethyl)-6-methoxy-7-methyl-2-phenyl-8-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol

: 122672-72-4
methyl 4,6-O-benzylidene-2-C-(2-(tert-butyldimethylsiloxy)ethyl)-2,3-dideoxy-3-C-(2-(N,N-dimethylcarbamoyl)methyl)-2-C-methyl-3-C-((E)-1-propenyl)-α-D-allopyranoside

Guidance literature:: Multi-step reaction with 9 steps

1: imidazole / tetrahydrofuran / 0.5 h / Ambient temperature

2: 69 percent / SOCl₂, pyridine / tetrahydrofuran / 1 h / 0 °C

3: dimethylformamide / 2 h / 100 °C

4: NaOMe / methanol / Ambient temperature

5: PCC, AcONa, Celite / CH₂Cl₂ / 0.33 h / Ambient temperature

6: tetrahydrofuran / 0.17 h

7: Ph₃P, diethyl azodicarboxylate / tetrahydrofuran / 0.08 h / Ambient temperature

8: MeLi / diethyl ether; tetrahydrofuran / 0.17 h / 0 °C

9: 70 percent / molecular sieves 4A / toluene / Heating

With pyridine; 1H-imidazole; thionyl chloride; 4 A molecular sieve; Celite; methyllithium; sodium methylate; sodium acetate; triphenylphosphine; pyridinium chlorochromate; diethylazodicarboxylate; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00283a034