4-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy}-N,N-dimethylaniline trihydrochloride

Base Information

Chemical Name:4-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy}-N,N-dimethylaniline trihydrochloride
CAS No.:104655-24-5
Molecular Formula:C22H31 N3 O2 . 3 Cl H
Molecular Weight:478.8833
Hs Code.:
Mol file:104655-24-5.mol

Synonyms:Benzenamine,4-[3-[4-(2-methoxyphenyl)-1-piperazinyl]propoxy]-N,N-dimethyl-,trihydrochloride (9CI)

Suppliers and Price of 4-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy}-N,N-dimethylaniline trihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 4-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy}-N,N-dimethylaniline trihydrochloride

Chemical Property:

Vapor Pressure:2.44E-11mmHg at 25°C
Boiling Point:530.5°C at 760 mmHg
Flash Point:149.1°C

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy}-N,N-dimethylaniline trihydrochloride

There total 4 articles about 4-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy}-N,N-dimethylaniline trihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 104655-10-9
N-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-N-methyl-formamide

: 104655-24-5
1-<4-(N,N-dimethylamino)phenoxy>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane hydrochloride

Guidance literature:: With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; 1.) THF, reflux, 2.) ether;

Reference yield:

: 104655-08-5
1-(4-aminophenoxy)-3-1-4-(2-methoxyphenyl)-piperazinyl>>propane

: 104655-24-5
1-<4-(N,N-dimethylamino)phenoxy>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / 8 h / Heating

2: 73 percent / 1.) LiAlH₄, 2.) HCl / tetrahydrofuran; diethyl ether / 1.) THF, 8h, reflux, 2.) ether

3: 80 percent / Heating

4: 80 percent / 1.) LiAlH₄, 2.) HCl / tetrahydrofuran; diethyl ether / 1.) THF, reflux, 2.) ether

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;

Reference yield:

: 104684-71-1
1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane

: 104655-24-5
1-<4-(N,N-dimethylamino)phenoxy>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / 1.) LiAlH₄, 2.) HCl / tetrahydrofuran; diethyl ether / 1.) THF, 8h, reflux, 2.) ether

2: 80 percent / Heating

3: 80 percent / 1.) LiAlH₄, 2.) HCl / tetrahydrofuran; diethyl ether / 1.) THF, reflux, 2.) ether

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;