3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

Base Information

Chemical Name:3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl
CAS No.:1352458-01-5
Molecular Formula:C₂₀H₂₂NO₄
Molecular Weight:340.399
Hs Code.:

Synonyms:3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

Suppliers and Price of 3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

There total 2 articles about 3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

: 1352458-00-4
3-(3,5-dimethoxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

: 1352458-01-5
3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

Guidance literature:: 3-(3,5-dimethoxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl; With hydrogenchloride; In ethanol; for 0.25h; Reflux;

With boron tribromide; In dichloromethane; at -78 - 20 ℃; for 48h;

With sodium hydrogencarbonate; In dichloromethane; chloroform; water; for 0.0833333h; Cooling with ice;
DOI:10.1016/j.bmc.2011.10.066

Reference yield:

: 1352457-97-6
3-bromo-4-(3,5-dimethoxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

: 71597-85-8
(p-hydroxyphenyl)boronic acid

: 1352458-01-5
3-(3,5-dihydroxyphenyl)-4-(4-hydroxyphenyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane; water / 4 h / Inert atmosphere; Reflux

1.2: pH 3

2.1: hydrogenchloride / ethanol / 0.25 h / Reflux

2.2: 48 h / -78 - 20 °C

2.3: 0.08 h / Cooling with ice

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; ethanol; water; 1.1: Suzuki coupling;
DOI:10.1016/j.bmc.2011.10.066