N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride

Base Information

Chemical Name:N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride
CAS No.:1380672-96-7
Molecular Formula:C₁₄H₉Cl₂F₃N₂O
Molecular Weight:349.139
Hs Code.:

Synonyms:N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride

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Chemical Property of N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride

Chemical Property:

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Technology Process of N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride

There total 4 articles about N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1380672-78-5
5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2-chloro-phenyl)-amide

: 1380672-96-7
N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride

Guidance literature:: With phosphorus pentachloride; In benzene; Reflux;

Reference yield:

: 30766-12-2
methyl 5-hydroxypicolinate

: 1380672-96-7
N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetonitrile

2: trimethylaluminum / toluene / 2 h / 80 - 90 °C

3: phosphorus pentachloride / benzene / Reflux

With phosphorus pentachloride; trimethylaluminum; potassium carbonate; In toluene; acetonitrile; benzene;

Reference yield:

: 1254199-82-0
5-(2,2,2-trifluoroethoxy)pyridine-2-carboxylic acid methyl ester

: 1380672-96-7
N-(2-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboximidoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: trimethylaluminum / toluene / 2 h / 80 - 90 °C

2: phosphorus pentachloride / benzene / Reflux

With phosphorus pentachloride; trimethylaluminum; In toluene; benzene;