3,5-Diphenyl-1H-pyrazole-1-propanoic acid

Base Information

Chemical Name:3,5-Diphenyl-1H-pyrazole-1-propanoic acid
CAS No.:94209-25-3
Molecular Formula:C₁₈H₁₆N₂O₂
Molecular Weight:292.337
Hs Code.:
DSSTox Substance ID:DTXSID401270616

Synonyms:3,5-Diphenyl-1H-pyrazole-1-propanoic acid;DTXSID401270616;94209-25-3

Suppliers and Price of 3,5-Diphenyl-1H-pyrazole-1-propanoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,5-Diphenyl-1H-pyrazole-1-propanoic acid

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:292.121177757
Heavy Atom Count:22
Complexity:362

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=NN2CCC(=O)O)C3=CC=CC=C3

Technology Process of 3,5-Diphenyl-1H-pyrazole-1-propanoic acid

There total 2 articles about 3,5-Diphenyl-1H-pyrazole-1-propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1437-14-5
3-(3,5-diphenyl-1H-pyrazol-1-yl)propanenitrile

: 94209-25-3
3-(3,5-diphenyl-1H-pyrazol-1-yl)propanoic acid

Guidance literature:: With hydrogenchloride; In water; for 3h; Heating;

Reference yield:

: 1145-01-3
3,5-Diphenylpyrazole

: 94209-25-3
3-(3,5-diphenyl-1H-pyrazol-1-yl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / 40percent Triton B / H₂O; dioxane / 0.5 h / 70 °C

2: 96 percent / conc HCl / H₂O / 3 h / Heating

With hydrogenchloride; N-benzyl-trimethylammonium hydroxide; In 1,4-dioxane; water;

Reference yield:

: 94209-25-3
3-(3,5-diphenyl-1H-pyrazol-1-yl)propanoic acid

: 130188-34-0
N,N-Diethyl 3-(3,5-diphenyl-1H-pyrazol-1-yl)propanamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1) SOCl₂ / 1) 5 min., heating; 2) benzene, a) r.t., 4 h, b) reflux, 1 h

2: 85 percent / LiAlH₄ / tetrahydrofuran / 24 h / Heating

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran;