(S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Base Information

Chemical Name:(S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide
CAS No.:380380-79-0
Molecular Formula:C₃₉H₃₇FN₆O₃
Molecular Weight:656.76
Hs Code.:

Synonyms:(S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

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Chemical Property of (S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Chemical Property:

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Technology Process of (S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

There total 4 articles about (S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 380380-57-4
2-(4-triphenylmethylpiperazin-1-yl)-5-iodopyrimidine

: 188975-86-2
N-({(5S)-3-[3-fluoro-4-(trimethylstannyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide

: 380380-79-0
(S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Guidance literature:: In N-methyl-acetamide; copper chloride; water;

Reference yield:

: 20980-22-7
N-(2-pyridinyl)piperazine

: 380380-79-0
(S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid; iodine; acetic acid / chloroform; water

2: methanol; dichloromethane; ethyl acetate; triethylamine

3: N-methyl-acetamide; copper chloride; water

With sulfuric acid; iodine; acetic acid; In N-methyl-acetamide; methanol; copper chloride; dichloromethane; chloroform; water; ethyl acetate; triethylamine;

Reference yield:

: 149524-45-8
(S)-N-[3-(3-fluoro-4-iodophenyl)-2-oxo-1,3-oxazolidine-5-ylmethyl]acetamide

: 380380-79-0
(S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hexamethyldistannane / 1,4-dioxane; dichlorobis(triphenylphosphine)palladium[II]

2: N-methyl-acetamide; copper chloride; water

With hexamethyldistannane; In 1,4-dioxane; N-methyl-acetamide; copper chloride; water; dichlorobis(triphenylphosphine)palladium[II];