Chemical Property of 2-Pyrimidinamine, 1,6-dihydro-6-imino-4-(1-piperidinyl)-1-(sulfooxy)-
Chemical Property:
- Appearance/Colour:white crystalline solid
- Vapor Pressure:1.71E-22mmHg at 25°C
- Melting Point:175-180 °C
- Boiling Point:732°C at 760 mmHg
- PKA:-4.99±0.18(Predicted)
- Flash Point:396.5oC
- PSA：146.86000
- Density:1.75±0.1 g/cm3(Predicted)
- LogP:0.72080
- Storage Temp.:−20°C
- Solubility.:Acetone (Slightly), DMSO (Slightly)
- XLogP3:0.9
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:3
- Exact Mass:289.08447515
- Heavy Atom Count:19
- Complexity:529
- Purity/Quality:
-
99% *data from raw suppliers
Minoxidil, Sulfate *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn,
T+
- Hazard Codes:Xn,T+
- Statements:
22-36/37/38-26/27/28
- Safety Statements:
26-36-45-36/37/39-22
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1CCN(CC1)C2=NC(=N)N(C(=C2)N)OS(=O)(=O)O
-
Uses
specifically opens ATP-sensitive K channels, strong vascular smooth muscle relaxer, active minoxidil metabolite Minoxidil sulfate (MXS) has been used as a drug agent to study its effects on alopecia in corticotropin-releasing factor over-expressing (CRF-OE) mice. It has also been used as a positive control in an assay for the culturing of rat vibrissa follicles. A selective ATP-sensitive potassium channel opener. It is the active metabolite of minoxidil and is a potent (IC50=0.14) vascular smooth muscle relaxant
-
Biological Functions
Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14M) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.
