LUCIFER YELLOW VS DILITHIUM SALT

Base Information

• Chemical Name: LUCIFER YELLOW VS DILITHIUM SALT
• CAS No.: 71231-14-6
• Molecular Formula: C20H14 N2 O10 S3 . 2 Li
• Molecular Weight: 550.403
• Mol file: 71231-14-6.mol

Synonyms:1H-Benz[de]isoquinoline-5,8-disulfonicacid, 6-amino-2-[3-(ethenylsulfonyl)phenyl]-2,3-dihydro-1,3-dioxo-, dilithiumsalt (9CI); Lucifer Yellow VS

Chemical Property of LUCIFER YELLOW VS DILITHIUM SALT

Chemical Property:

• Melting Point: >200 ℃
• PSA: 233.11000
• LogP: 4.75830
• Storage Temp.: 2-8°C
• Solubility.: Soluble in water; insoluble in ethanol

Purity/Quality:

99% ^*data from raw suppliers

Lucifer Yellow VS Dilithium Salt ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Fluoroprobe for biological tracing. Lucifer Yellow VS Dilithium Salt is a highly fluorescent dye used for labeling proteins. It can also be used in analytical study of dual analyte flow injection fluorescence immunoassays using thiophilic gel reactors and synchronous scanning detection. Dyes and metabolites.

Technology Process of LUCIFER YELLOW VS DILITHIUM SALT

There total 7 articles about LUCIFER YELLOW VS DILITHIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium 4-amino-N-(4-methylphenyl)naphthalimide-3-sulfonate (2391-30-2) → dilithium 4-amino-N-[3-(vinylsulfonyl)phenyl]-naphthalimide-3,6-disulfonate (71231-14-6)

Guidance literature:

Multi-step reaction with 6 steps

1: fuming H₂SO₄ / 3 h / 90 °C

2: 1.) aq. KOH, 2.) aq. HCl / 1) pH 12.5, 50 deg C, 10 min; 2) pH 2.0, 50 deg C, 10 min; 3) pH 2, 3 d, room temperature

3: 79 percent / H₂O / 48 h

4: 1.) aq. H₂SO₄, 2.) aq. KCl / 1) 4 deg C, 24 h; 2) 50 deg C

5: 97 percent / aq. NaOH / 0.25 h / Ambient temperature; pH 10

6: 8.95 g / Dowex 50W-X₂

With hydrogenchloride; potassium hydroxide; sodium hydroxide; DOWEX 50W-X₂; sulfuric acid; potassium chloride; In water;

DOI:10.1021/ja00415a033

Reference yield:

3-aminophenyl 2-hydroxy-ethyl sulphone (5246-57-1) → dilithium 4-amino-N-[3-(vinylsulfonyl)phenyl]-naphthalimide-3,6-disulfonate (71231-14-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 79 percent / H₂O / 48 h

2: 1.) aq. H₂SO₄, 2.) aq. KCl / 1) 4 deg C, 24 h; 2) 50 deg C

3: 97 percent / aq. NaOH / 0.25 h / Ambient temperature; pH 10

4: 8.95 g / Dowex 50W-X₂

With sodium hydroxide; DOWEX 50W-X₂; sulfuric acid; potassium chloride; In water;

DOI:10.1021/ja00415a033

Reference yield:

4-amino-3,6-disulfo-1,8-naphthaldehyde anhydride dipotassium salt (79539-35-8) → dilithium 4-amino-N-[3-(vinylsulfonyl)phenyl]-naphthalimide-3,6-disulfonate (71231-14-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 79 percent / H₂O / 48 h

2: 1.) aq. H₂SO₄, 2.) aq. KCl / 1) 4 deg C, 24 h; 2) 50 deg C

3: 97 percent / aq. NaOH / 0.25 h / Ambient temperature; pH 10

4: 8.95 g / Dowex 50W-X₂

With sodium hydroxide; DOWEX 50W-X₂; sulfuric acid; potassium chloride; In water;

DOI:10.1021/ja00415a033

upstream raw materials:

potassium salt of Lucifer Yellow VS

3-aminophenyl 2-hydroxy-ethyl sulphone

sodium 4-amino-N-(4-methylphenyl)naphthalimide-3-sulfonate

4-amino-3,6-disulfo-1,8-naphthaldehyde anhydride dipotassium salt

Refernces