Technology Process of 2-(3,4-dihydro-6,7-methylenedioxy-2-naphthyl)-3,4-dimethoxybenzaldehyde
There total 8 articles about 2-(3,4-dihydro-6,7-methylenedioxy-2-naphthyl)-3,4-dimethoxybenzaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate;
In
methanol; N,N-dimethyl-formamide;
at 80 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1016/j.tet.2010.11.066
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 1 h / 80 °C
2: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / methanol; N,N-dimethyl-formamide / 0.5 h / 80 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; potassium carbonate;
In
methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
2: Suzuki-Miyaura reaction;
DOI:10.1016/j.tet.2010.11.066
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: Grubbs catalyst first generation / dichloromethane / 1 h / 50 °C / Inert atmosphere
2.1: borane-THF / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
2.2: 1 h / 50 °C
3.1: pyridinium chlorochromate / 1.5 h / 20 °C / Inert atmosphere
4.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
4.2: 4 h / -78 - 20 °C / Inert atmosphere
5.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 1 h / 80 °C
6.1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / methanol; N,N-dimethyl-formamide / 0.5 h / 80 °C / Inert atmosphere
With
Grubbs catalyst first generation; bis-triphenylphosphine-palladium(II) chloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; borane-THF; potassium acetate; potassium carbonate; pyridinium chlorochromate; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
1.1: olefin metathesis / 6.1: Suzuki-Miyaura reaction;
DOI:10.1016/j.tet.2010.11.066
