8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide

Base Information

• Chemical Name: 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide
• CAS No.: 50330-61-5
• Molecular Formula: C₁₉H₁₅ClFN₅O
• Molecular Weight: 383.812

Synonyms:8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide

Chemical Property of 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide

There total 4 articles about 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-chloro-6-(2-fluorophenyl)-4H-[1,2,4]triazolo[1,5-a][1,4]benzodiazepine-2-carboxylic acid (40408-66-0) → 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid diethylamide (50330-60-4) + 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide (50330-61-5)

Guidance literature:

In isopropyl alcohol;

Reference yield:

N,N-dimethyl-1-[2-(o-fluorobenzoyl)-4-chlorophenyl]-5-(chloromethyl)-1H-1,2,4-triazole-3-carboxamide (58092-69-6) → 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide (50330-61-5)

Guidance literature:

Reference yield:

→ 8-chloro-6-(2-fluoro-phenyl)-4H-benzo[f][1,2,4]triazolo[1,5-a][1,4]diazepine-2-carboxylic acid dimethylamide (50330-61-5)

Guidance literature:

Natriumsalz 5a 1)Oxalylchlorid,2)Dimethylamin;

DOI:10.1002/hlca.19780610233

upstream raw materials:

8-chloro-6-(2-fluorophenyl)-4H-[1,2,4]triazolo[1,5-a][1,4]benzodiazepine-2-carboxylic acid

N,N-dimethyl-1-[2-(o-fluorobenzoyl)-4-chlorophenyl]-5-(chloromethyl)-1H-1,2,4-triazole-3-carboxamide

Downstream raw materials:

2,12,12-trichloro-13a-(2-fluoro-phenyl)-11-oxo-11,12-dihydro-9H,13aH-benzo[f]oxazolo[3,2-d][1,2,4]triazolo[1,5-a][1,4]diazepine-7-carboxylic acid dimethylamide

2,12t-dichloro-13a-(2-fluoro-phenyl)-9t-methoxy-11-oxo-11,12-dihydro-(13ar)-9H,13aH-benzo[f]oxazolo[3,2-d][1,2,4]triazolo[1,5-a][1,4]diazepine-7-carboxylic acid dimethylamide

2-chloro-13a-(2-fluoro-phenyl)-9t,12t-dimethoxy-11-oxo-11,12-dihydro-(13ar)-9H,13aH-benzo[f]oxazolo[3,2-d][1,2,4]triazolo[1,5-a][1,4]diazepine-7-carboxylic acid dimethylamide

2-chloro-13a-(2-fluoro-phenyl)-9t,12c-dimethoxy-11-oxo-11,12-dihydro-(13ar)-9H,13aH-benzo[f]oxazolo[3,2-d][1,2,4]triazolo[1,5-a][1,4]diazepine-7-carboxylic acid dimethylamide

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