Technology Process of ethyl 3R,5S-6-(benzyloxy)-3,5-dihydroxy hexanoate
There total 8 articles about ethyl 3R,5S-6-(benzyloxy)-3,5-dihydroxy hexanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: pyridine / CH2Cl2 / 20 °C
2: imidazole / dimethylformamide / 20 °C
3: trifluoroacetic acid / CH2Cl2; H2O / -20 °C
4: pyridinium chlorochromate, 4A molecular sieves / CH2Cl2
5: Zn, diethylaluminium chloride / tetrahydrofuran / 0.33 h / 15 °C / other reagent: chlorotitanium triisopropoxide
6: Bu4NF, CH3COOH / tetrahydrofuran / 20 °C
With
pyridine; 1H-imidazole; 4 A molecular sieve; tetrabutyl ammonium fluoride; diethylaluminium chloride; acetic acid; pyridinium chlorochromate; trifluoroacetic acid; zinc;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)91028-7
- Guidance literature:
-
Multi-step reaction with 7 steps
1: Red-Al / tetrahydrofuran / 0 °C
2: pyridine / CH2Cl2 / 20 °C
3: imidazole / dimethylformamide / 20 °C
4: trifluoroacetic acid / CH2Cl2; H2O / -20 °C
5: pyridinium chlorochromate, 4A molecular sieves / CH2Cl2
6: Zn, diethylaluminium chloride / tetrahydrofuran / 0.33 h / 15 °C / other reagent: chlorotitanium triisopropoxide
7: Bu4NF, CH3COOH / tetrahydrofuran / 20 °C
With
pyridine; 1H-imidazole; 4 A molecular sieve; tetrabutyl ammonium fluoride; diethylaluminium chloride; acetic acid; sodium bis(2-methoxyethoxy)aluminium dihydride; pyridinium chlorochromate; trifluoroacetic acid; zinc;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)91028-7
