2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

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Chemical Name:2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide
CAS No.:1361952-84-2
Molecular Formula:C₂₉H₃₄N₄O₃
Molecular Weight:486.614
Hs Code.:

Synonyms:2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

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Chemical Property of 2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

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Technology Process of 2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

There total 1 articles about 2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-[(S)-1-(2-aminoethyl)pyrrolidin-3-yl]-2,2-diphenylacetamide

: 40896-62-6
(3-Aminomethylphenyl)methanol Hydrochloride

: 530-62-1
1,1'-carbonyldiimidazole

: 1361952-84-2
2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

Guidance literature:: 2-[(S)-1-(2-aminoethyl)pyrrolidin-3-yl]-2,2-diphenylacetamide; 1,1'-carbonyldiimidazole; With N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 2h;

(3-Aminomethylphenyl)methanol Hydrochloride; With N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 50 ℃; for 12h;

Reference yield:

: 1361952-84-2
2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

: 2-((S)-1-{2-[3-(3-formylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

Guidance literature:: 2-((S)-1-{2-[3-(3-hydroxymethylbenzyl)ureido]ethyl}pyrrolidin-3-yl)-2,2-diphenylacetamide; With dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 0.166667h;

With sulfur trioxide pyridine complex; In dichloromethane; at 0 ℃; for 2h;