2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole

Base Information

• Chemical Name: 2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole
• CAS No.: 1416470-72-8
• Molecular Formula: C₂₆H₂₅N₂PS
• Molecular Weight: 428.538
• Mol file: 1416470-72-8.mol

Synonyms:2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole

Chemical Property of 2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole

There total 1 articles about 2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2,5-bis{3-[(diphenylmethylene)amino]phenyl}-1-phenyl-1-thiooxophosphole (1416470-70-6) → 2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole (1416470-72-8)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; for 3h; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201201148

Reference yield: 62.0%

2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole (1416470-72-8) → 2,5-bis(3-azidophenyl)-1-phenyl-1-thiooxophosphole

Guidance literature:

2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole; With hydrogenchloride; sodium nitrite; In tetrahydrofuran; water; at -5 ℃; for 0.333333h; Inert atmosphere;

With sodium azide; sodium acetate; In tetrahydrofuran; water; at -5 ℃; for 2h; Inert atmosphere;

DOI:10.1002/ejoc.201201148

Reference yield:

2,5-bis(3-aminophenyl)-1-phenyl-1-thiooxophosphole (1416470-72-8) → 2,5-bis[4-(pyridin-2-yl)-1H-1,2,3-triazol-1-yl]-1-phenylphosphole

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride; sodium nitrite / tetrahydrofuran; water / 0.33 h / -5 °C / Inert atmosphere

1.2: 2 h / -5 °C / Inert atmosphere

2.1: 2,6-dimethylpyridine; tetrakis(actonitrile)copper(I) hexafluorophosphate / dichloromethane / 64 h / 20 °C / Inert atmosphere

3.1: Hexamethylphosphorous triamide / tetrahydrofuran; toluene / 16 h / Inert atmosphere; Reflux

With 2,6-dimethylpyridine; hydrogenchloride; tetrakis(actonitrile)copper(I) hexafluorophosphate; sodium nitrite; Hexamethylphosphorous triamide; In tetrahydrofuran; dichloromethane; water; toluene; 1.1: |Huisgen Cycloaddition;

DOI:10.1002/ejoc.201201148

upstream raw materials:

2,5-bis{3-[(diphenylmethylene)amino]phenyl}-1-phenyl-1-thiooxophosphole