methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate

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Chemical Name:methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate
CAS No.:1210047-73-6
Molecular Formula:C₂₈H₂₃F₂N₅O₃
Molecular Weight:515.519
Hs Code.:

Synonyms:methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate

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Chemical Property of methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate

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Technology Process of methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate

There total 1 articles about methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 705279-03-4
methyl 2-bromo-5-(difluoromethoxy)benzenecarboxylate

: 1210047-26-9
4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazole-5-amine

: 1210047-73-6
methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate

Guidance literature:: 4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazole-5-amine; palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; In toluene; at 20 ℃; for 0.0833333h; Inert atmosphere;

methyl 2-bromo-5-(difluoromethoxy)benzenecarboxylate; With caesium carbonate; In toluene; at 95 ℃; Inert atmosphere;

Reference yield: 90.0%

: 1210047-73-6
methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate

: 1210048-84-2
2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzoic acid

Guidance literature:: methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-(difluoromethoxy)benzenecarboxylate; With water; sodium hydroxide; In 1,4-dioxane; at 20 ℃;

With hydrogenchloride; In water;