Urea, 1-(1-naphthyl)-3-phenyl-

Base Information

• Chemical Name: Urea, 1-(1-naphthyl)-3-phenyl-
• CAS No.: 5031-71-0
• Molecular Formula: C17H14N2O
• Molecular Weight: 262.311
• Hs Code.: 2924299090
• European Community (EC) Number: 653-484-6
• NSC Number: 44660
• DSSTox Substance ID: DTXSID40964596
• Nikkaji Number: J104.980A
• ChEMBL ID: CHEMBL1342673
• Mol file: 5031-71-0.mol

Synonyms:5031-71-0;Urea, 1-(1-naphthyl)-3-phenyl-;1-(naphthalen-1-yl)-3-phenylurea;Urea, N-1-naphthalenyl-N'-phenyl-;1-NAPHTHALEN-1-YL-3-PHENYL-UREA;1-(1-naphthyl)-3-phenylurea;NSC44660;TimTec1_002308;Oprea1_513864;Oprea1_578425;CBDivE_006734;MLS001018092;SCHEMBL6673848;CHEMBL1342673;N-(1-Naphthyl)-N'-phenylurea;DTXSID40964596;HXIKAEAULDUNBD-UHFFFAOYSA-N;HMS1540I20;HMS2756C11;N-(1-Naphthyl)-N'-phenylurea #;NSC-44660;AKOS001033921;SMR000354332;N-Naphthalen-1-yl-N'-phenylcarbamimidic acid;BRD-K47999570-001-01-1;Z44586341;F3147-4003

Chemical Property of Urea, 1-(1-naphthyl)-3-phenyl-

Chemical Property:

• Vapor Pressure: 2.34E-05mmHg at 25°C
• Boiling Point: 359.6°Cat760mmHg
• Flash Point: 126.1°C
• PSA: 41.13000
• Density: 1.286g/cm³
• LogP: 4.62980
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 262.110613074
• Heavy Atom Count: 20
• Complexity: 325

Purity/Quality:

99%min ^*data from raw suppliers

1-NAPHTHALEN-1-YL-3-PHENYL-UREA 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)NC2=CC=CC3=CC=CC=C32

Technology Process of Urea, 1-(1-naphthyl)-3-phenyl-

There total 11 articles about Urea, 1-(1-naphthyl)-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-amino-naphthalene (134-32-7) + aniline (62-53-3) → N-(1-naphthalenyl)-N'-phenyl-urea (5031-71-0)

Guidance literature:

1-amino-naphthalene; With bis(trichloromethyl) carbonate; triethylamine; In dichloromethane; at 20 ℃; for 0.5h;

aniline; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield: 85.0%

1-Iodonaphthalene (90-14-2) + phenyl carbamate (64-10-8) → N-(1-naphthalenyl)-N'-phenyl-urea (5031-71-0)

Guidance literature:

With potassium phosphate; copper(l) iodide; N,N`-dimethylethylenediamine; In N,N-dimethyl-formamide; at 85 ℃; for 24h;

DOI:10.1016/j.cclet.2010.12.018

Reference yield: 82.0%

phenyl carbamate (64-10-8) + 1-Naphthylboronic acid (13922-41-3) → N-(1-naphthalenyl)-N'-phenyl-urea (5031-71-0)

Guidance literature:

With copper acetylacetonate; potassium tert-butylate; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 24h; Inert atmosphere; Sealed vial;

DOI:10.1080/00397911.2010.543747

upstream raw materials:

N-carboethoxyaniline

1-amino-naphthalene

1-Iodonaphthalene

phenyl carbamate

Refernces

• 1、 Sribalan, Rajendran,Sangili, Arumugam,Banuppriya, Govindharasu,Padmini, Vediappen. "An efficient synthesis of nitrile, tetrazole and urea from carbonyl compounds". . p. 3414 - 3421. Retrieved 2017/07/13.
• 2、 Hosseinzadeh, Rahman,Tajbakhsh, Mahmood,Aghili, Nora. "Synthesis of unsymmetrical ureas and S-thiocarbamates under catalyst-free conditions in a [BMIM]BF4 ionic liquid". . p. 175 - 182. Retrieved 2015/05/27.