2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde

Base Information

• Chemical Name: 2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde
• CAS No.: 78835-25-3
• Molecular Formula: C₂₅H₃₆O₄
• Molecular Weight: 400.558
• Mol file: 78835-25-3.mol

Synonyms:2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde

Chemical Property of 2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde

There total 1 articles about 2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

siphonodictyal-B + dimethyl sulfate (77-78-1) → 2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde (78835-25-3)

Guidance literature:

With potassium carbonate; In acetone; at 80 ℃;

DOI:10.1016/S0040-4020(01)97672-0

Reference yield:

2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde (78835-25-3) → [2,4,5-Trimethoxy-3-((1S,2S,8aR)-2,5,5,8a-tetramethyl-decahydro-naphthalen-1-ylmethyl)-phenyl]-methanol (78835-29-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In diethyl ether; Yield given;

DOI:10.1016/S0040-4020(01)97672-0

Reference yield:

2,4,5-Trimethoxy-3-[(2S,8aS)-2,5,5,8a-tetramethyl-octahydro-naphthalen-(1E)-ylidenemethyl]-benzaldehyde (78835-25-3) → 9,11-dihydrosiphonodictyal-B trimethyl ether (78835-30-0)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 10percent Pd-C / diethyl ether

2: 80 percent / MnO₂ / acetone / 5 h / 25 °C

With manganese(IV) oxide; hydrogen; palladium on activated charcoal; In diethyl ether; acetone;

DOI:10.1016/S0040-4020(01)97672-0

upstream raw materials:

dimethyl sulfate

Downstream raw materials:

2α,5,5,8aβ-Tetramethyl-decalon-(1)

3-formyl-2,4,5-trimethoxybenzaldehyde

[2,4,5-Trimethoxy-3-((1S,2S,8aR)-2,5,5,8a-tetramethyl-decahydro-naphthalen-1-ylmethyl)-phenyl]-methanol

9,11-dihydrosiphonodictyal-B trimethyl ether