2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

Base Information

Chemical Name:2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester
CAS No.:849359-34-8
Molecular Formula:C₅₄H₅₄N₂O₉
Molecular Weight:875.031
Hs Code.:

Synonyms:2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

Suppliers and Price of 2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

There total 6 articles about 2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 104597-98-0
(S)-2-methoxycarbonyl-1-benzyloxycarbonylaziridine

: 849359-28-0
2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-1H-indole

: 849359-34-8
2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

Guidance literature:: With scandium(III) perchlorate; 5A molecular sieve; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1039/b414905j

Reference yield:

: 56822-48-1
(2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-yl acetate

: 849359-34-8
2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: TMSOTf / CH₂Cl₂ / 18 h / 4 °C

2: 0.71 g / K₂CO₃ / methanol / 1 h / 20 °C

3: 44 percent / Ph₃P; CuI; n-BuNH₂ / Pd₂[dba]3*CHCl₃ / tetrahydrofuran / 60 °C

4: 98 percent / n-Bu₄NF / tetrahydrofuran / 0.83 h / 20 °C

5: 41 percent / Sc(ClO₄)3; 5 Angstroem molecular sieves / CH₂Cl₂ / 2 h / 0 °C

With copper(l) iodide; scandium(III) perchlorate; trimethylsilyl trifluoromethanesulfonate; 5A molecular sieve; tetrabutyl ammonium fluoride; potassium carbonate; N-butylamine; triphenylphosphine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; methanol; dichloromethane; 3: Sonogashira coupling;
DOI:10.1039/b414905j

Reference yield:

: 139195-28-1
(2R,3R,4R,5S,6R)-3,4,5-tribenzyloxy-2-(benzyloxymethyl)-6-ethynyltetrahydropyran

: 849359-34-8
2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-(N-carbobenzyloxy)tryptophan methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 44 percent / Ph₃P; CuI; n-BuNH₂ / Pd₂[dba]3*CHCl₃ / tetrahydrofuran / 60 °C

2: 98 percent / n-Bu₄NF / tetrahydrofuran / 0.83 h / 20 °C

3: 41 percent / Sc(ClO₄)3; 5 Angstroem molecular sieves / CH₂Cl₂ / 2 h / 0 °C

With copper(l) iodide; scandium(III) perchlorate; 5A molecular sieve; tetrabutyl ammonium fluoride; N-butylamine; triphenylphosphine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; dichloromethane; 1: Sonogashira coupling;
DOI:10.1039/b414905j