4-benzoyl-1-indancarboxylic acid

Base Information

• Chemical Name: 4-benzoyl-1-indancarboxylic acid
• CAS No.: 56461-33-7
• Molecular Formula: C17H14 O3
• Molecular Weight: 266.29
• Mol file: 56461-33-7.mol

Synonyms:4-Benzoylindan-1-carboxylicacid; TAI 901

Chemical Property of 4-benzoyl-1-indancarboxylic acid

Chemical Property:

• Vapor Pressure: 3.52E-11mmHg at 25°C
• Boiling Point: 508.9°C at 760 mmHg
• Flash Point: 275.7°C
• PSA: 54.37000
• Density: 1.274g/cm³
• LogP: 3.03200

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-benzoyl-1-indancarboxylic acid

There total 5 articles about 4-benzoyl-1-indancarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-benzoylindan-1-carbonitrile (56486-31-8) → 4-benzoyl-1-indancarboxylic acid (56461-33-7)

Guidance literature:

With sulfuric acid; potassium carbonate; In nitrogen; water;

Reference yield:

ethyl 4-benzoylindan-1-carboxylate (56461-72-4) → 4-benzoyl-1-indancarboxylic acid (56461-33-7)

Guidance literature:

With potassium hydroxide; In ethanol; water;

Reference yield:

4-benzylindan-1-carboxylic acid (56461-64-4) → 4-benzoyl-1-indancarboxylic acid (56461-33-7)

Guidance literature:

With selenium(IV) oxide; In 1,4-dioxane; chloroform; cyclohexane; water; benzene;

upstream raw materials:

4-benzoylindan-1-carbonitrile

4-benzoylindan-1-carboxamide

ethyl 4-benzoylindan-1-carboxylate

4-benzylindan-1-carboxylic acid

Downstream raw materials:

4-(4-benzoyl-indan-1-carbonyl)-morpholine

N-methyl-4-benzoylindan-1-carboxamide

4-benzoylindan-1-carboxamide

ethyl 4-benzoylindan-1-carboxylate

Refernces

• 1、 Aono,Araki,Imanishi,Noguchi. "1-Indancarboxylic acids. II. Synthesis of 4- and 6-aroyl-1-indancarboxylic acids as potential antiinflammatory agents". . p. 1153 - 1161,1154,1158. Retrieved 2007/10/13.