2-(4-TERT-BUTYLPHENOXY)PROPANOIC ACID

Base Information

• Chemical Name: 2-(4-TERT-BUTYLPHENOXY)PROPANOIC ACID
• CAS No.: 6941-12-4
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.284
• Hs Code.: 2918990090
• Mol file: 6941-12-4.mol

Synonyms:2-(3,4-DIMETHOXY-PHENYL)-IMIDAZO[1,2-A]PYRIDINE-3;2-(4-tert-Butyl-phenoxy)-propionsaeure;2-(4-t-Butylphenoxy)propionic acid;Propanoic acid, 2-[4-(1,1-dimethylethyl)phenoxy]-;O-(4-tert.-Butyl-phenyl)-DL-milchsaeure;2-[4-(1,1-dimethylethyl)phenoxy]-propanoic acid;2-(p-tert-butylphenoxy)propionic acid;2-(4-tert-butyl-phenoxy)-propionic acid;2-[4-(tert-butyl)phenoxy]propanoic acid;

Chemical Property of 2-(4-TERT-BUTYLPHENOXY)PROPANOIC ACID

Chemical Property:

• Vapor Pressure: 5.19E-05mmHg at 25°C
• Boiling Point: 334°C at 760 mmHg
• Flash Point: 121°C
• PSA: 46.53000
• LogP: 2.83600

Purity/Quality:

99% ^*data from raw suppliers

2-[4-(tert-Butyl)phenoxy]propanoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-TERT-BUTYLPHENOXY)PROPANOIC ACID

There total 3 articles about 2-(4-TERT-BUTYLPHENOXY)PROPANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

para-tert-butylphenol (98-54-4) + 2-Bromopropionic acid (598-72-1,10327-08-9) → 2-(p-tert-butylphenoxy)propionic acid (6941-12-4,16453-52-4,16453-53-5)

Guidance literature:

para-tert-butylphenol; With sodium hydride; In N,N-dimethyl-formamide; at 25 - 30 ℃; for 0.5h;

2-Bromopropionic acid; In N,N-dimethyl-formamide; at 20 - 25 ℃; for 4h;

DOI:10.1039/c5gc00156k

Reference yield:

(R,S)-2-chloropropionic acid (598-78-7) → 2-(p-tert-butylphenoxy)propionic acid (6941-12-4,16453-52-4,16453-53-5)

Guidance literature:

With sodium hydroxide; ethanol;

Reference yield:

→ 2-(p-tert-butylphenoxy)propionic acid (6941-12-4,16453-52-4,16453-53-5)

Guidance literature:

upstream raw materials:

para-tert-butylphenol

2-Bromopropionic acid

(R,S)-2-chloropropionic acid

Downstream raw materials:

6β-[(Ξ)-2-(4-tert-butyl-phenoxy)-propionylamino]-penicillanic acid

(R)-2-(4-tert-butylphenoxy)propionic acid

(S)-2-(4-tert-butylphenoxy)propionic acid

C₂₆H₂₃BrClF₃N₂O₃