3-methoxy-17¹-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate

Base Information

• Chemical Name: 3-methoxy-17¹-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate
• CAS No.: 127477-01-4
• Molecular Formula: C₃₀H₃₄O₅S
• Molecular Weight: 506.663

Synonyms:3-methoxy-17¹-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate

Chemical Property of 3-methoxy-17¹-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methoxy-17¹-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate

There total 3 articles about 3-methoxy-17¹-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

PVS (5535-48-8) + 3-methoxy-16-methylestra-1,3,5(10),14,16-pentaen-17-yl acetate (127460-95-1) → 3-methoxy-171-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate (127477-01-4) + 3-meethoxy-171-methyl-15α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate (127460-96-2,127515-86-0) + (172R)-3-methoxy-16-methyl-172-phenylsulphonyl-14,17α-ethanoestra-1,3,5(10),15-tetraen-17β-yl acetate (127460-96-2,127515-86-0)

Guidance literature:

In xylene; at 140 ℃; for 120h; Yield given;

DOI:10.1039/P19910002859

Reference yield: 14.0%

PVS (5535-48-8) + 3-methoxy-16-methylestra-1,3,5(10),14,16-pentaen-17-yl acetate → C30H34O5S (127477-01-4) + C30H34O5S + C30H34O5S

Guidance literature:

In xylene; at 140 ℃; for 120h;

DOI:10.1039/c39890001405

Reference yield:

3-methoxy-16-methylestra-1,3,5(10),15-tetraen-17-one (81480-80-0) → 3-methoxy-171-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate (127477-01-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / isopropenyl acetate, p-TsOH / 20 h / 100 °C

2: xylene / 120 h / 140 °C

With Isopropenyl acetate; toluene-4-sulfonic acid; In xylene;

DOI:10.1039/P19910002859

upstream raw materials:

PVS

3-methoxy-16-methylestra-1,3,5⁽¹⁰⁾,14,16-pentaen-17-yl acetate

3-methoxy-16-methylestra-1,3,5⁽¹⁰⁾,15-tetraen-17-one

Downstream raw materials:

3-methoxy-16-methyl-14-(2-phenylsulphonylethyl)-14β-estra-1,3,5(10),15-tetraen-17-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 127477-01-4 3-methoxy-17¹-methyl-16α-phenylsulphonyl-14,17α-ethenoestra-1,3,5(10)-trien-17β-yl acetate

Send

Send

Metric Ton KG G Pound L ML

Send

Send