C₂₁H₂₆N₄OS

Base Information

• Chemical Name: C₂₁H₂₆N₄OS
• CAS No.: 1261359-89-0
• Molecular Formula: C₂₁H₂₆N₄OS
• Molecular Weight: 382.53
• Mol file: 1261359-89-0.mol

Synonyms:C₂₁H₂₆N₄OS

Chemical Property of C₂₁H₂₆N₄OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₂₆N₄OS

There total 4 articles about C₂₁H₂₆N₄OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,7-heptanediol monobenzyl ether (141943-06-8) + 1-Phenyl-1H-tetrazole-5-thiol (86-93-1) → C21H26N4OS (1261359-89-0)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 4h; Inert atmosphere;

DOI:10.1002/chem.201204527

Reference yield: 98.0%

1H-mercaptophenyltetrazole (81949-25-9) + 1,7-heptanediol monobenzyl ether (141943-06-8) → C21H26N4OS (1261359-89-0)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 4h;

DOI:10.1021/ol1028699

Reference yield:

1,7-heptandiol (629-30-1) → C21H26N4OS (1261359-89-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 10 h / 0 - 20 °C / Inert atmosphere

2.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 6 h / 0 - 20 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; sodium hydride; triphenylphosphine; In tetrahydrofuran;

DOI:10.1021/acs.orglett.9b03857

upstream raw materials:

1H-mercaptophenyltetrazole

1,7-heptanediol monobenzyl ether

1-Phenyl-1H-tetrazole-5-thiol

1,7-heptandiol

Downstream raw materials:

C₂₁H₂₆N₄O₃S

C₁₉H₂₈O₂

C₁₉H₃₀O₄

C₃₁H₅₈O₄Si₂