1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

Base Information

Chemical Name:1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol
CAS No.:43076-28-4
Molecular Formula:C₂₉H₃₅NO₃
Molecular Weight:445.602
Hs Code.:

Synonyms:1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

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Technology Process of 1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

There total 2 articles about 1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-one

: 43076-28-4
1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃; for 3h;
DOI:10.1021/jm5010682

Reference yield:

: 115-46-8
C₁₈H₂₁NO

: 40877-19-8
4-chloro-1-(4-methoxyphenyl)butan-1-one

: 43076-28-4
1-(4-methoxyphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / water; butanone / 16 h / 85 °C

2: sodium tetrahydroborate / methanol / 3 h / 20 °C

With sodium tetrahydroborate; sodium hydrogencarbonate; In methanol; water; butanone;
DOI:10.1021/jm5010682