1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole

Base Information

Chemical Name:1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole
CAS No.:1207741-43-2
Molecular Formula:C₁₇H₁₃ClF₃N₃O
Molecular Weight:367.758
Hs Code.:

Synonyms:1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole

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Technology Process of 1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole

There total 1 articles about 1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 1115300-94-1
1-azido-2-chloro-4-(trifluoromethyl)benzene

: 122-84-9
4-methoxybenzyl methyl ketone

: 1207741-43-2
1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole

Guidance literature:: With sodium methylate; In methanol; at 0 ℃; Inert atmosphere; Reflux;

Reference yield: 91.0%

: 1207741-43-2
1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole

: 1207741-44-3
4-[1-(2-chloro-4-trifluoromethyl-phenyl)-5-methyl-1H-[1,2,3]triazol-4-yl]-phenol

Guidance literature:: 1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-5-methyl-1H-[1,2,3]triazole; With boron tribromide; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

With methanol; water; In dichloromethane; Cooling with ice-salt bath;