3-cyanobenzenesulfonyl fluoride

Base Information

• Chemical Name: 3-cyanobenzenesulfonyl fluoride
• CAS No.: 402-27-7
• Molecular Formula: C₇H₄FNO₂S
• Molecular Weight: 185.179
• Mol file: 402-27-7.mol

Synonyms:3-cyanobenzenesulfonyl fluoride

Chemical Property of 3-cyanobenzenesulfonyl fluoride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-cyanobenzenesulfonyl fluoride

There total 4 articles about 3-cyanobenzenesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

→ 3-cyanobenzenesulfonyl fluoride (402-27-7)

Guidance literature:

Reference yield: 72.0%

3-cyanobenzenediazonium tetrafluoroborate → 3-cyanobenzenesulfonyl fluoride (402-27-7)

Guidance literature:

With sodium metabisulfite; N-fluorobis(benzenesulfon)imide; In water; acetonitrile; at 60 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.jfluchem.2020.109653

Reference yield:

m-cyanoaniline (2237-30-1) → 3-cyanobenzenesulfonyl fluoride (402-27-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: water / 0.25 h / 0 °C

1.2: 0.5 h / 0 °C

2.1: sodium metabisulfite; N-fluorobis(benzenesulfon)imide / water; acetonitrile / 6 h / 60 °C / Inert atmosphere

With sodium metabisulfite; N-fluorobis(benzenesulfon)imide; In water; acetonitrile; 2.1: |Sandmeyer Reaction;

DOI:10.1016/j.jfluchem.2020.109653

upstream raw materials:

m-cyanoaniline