N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

Base Information

Chemical Name:N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester
CAS No.:821005-94-1
Molecular Formula:C₅₂H₅₈INO₂₁
Molecular Weight:1159.93
Hs Code.:

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

Synonyms:N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

Suppliers and Price of N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

There total 2 articles about N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 118358-66-0,73724-46-6
N-(9-fluorenylmethyloxycarbonyl)-L-serine benzyl ester

: 4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-3-deoxy-D-galactal

: 821005-94-1
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

Guidance literature:: With iodonium(di-γ-collidine) perchlorate; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1016/j.tetasy.2004.09.029

Reference yield:

: 1,4,6-tri-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-D-lyxo-hexopyranose

: 821005-94-1
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-{4,6-di-O-acetyl-3-C-[(1R)-1,3,4,5,7-penta-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptitol-1-C-yl]-2,3-dideoxy-2-iodo-α-D-talo-pyranosyl}-L-serine phenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / silica gel / toluene / 6 h / Heating

2: 70 percent / I(sym-collidine)2ClO₄ / CH₂Cl₂ / 2 h / 20 °C

With iodonium(di-γ-collidine) perchlorate; silica gel; In dichloromethane; toluene;
DOI:10.1016/j.tetasy.2004.09.029