2-ethylcyclohexa-2,5-diene-1,4-dione

Base Information

• Chemical Name: 2-ethylcyclohexa-2,5-diene-1,4-dione
• CAS No.: 4754-26-1
• Molecular Formula: C8H8 O2
• Molecular Weight: 136.15
• Mol file: 4754-26-1.mol

Synonyms:p-Benzoquinone,2-ethyl- (8CI); p-Benzoquinone, ethyl- (6CI,7CI); 2-Ethyl-1,4-benzoquinone;2-Ethyl-2,5-cyclohexadiene-1,4-dione; 2-Ethyl-p-benzoquinone;2-Ethylbenzoquinone; 2-Ethylquinone

Chemical Property of 2-ethylcyclohexa-2,5-diene-1,4-dione

Chemical Property:

• Vapor Pressure: 0.243mmHg at 25°C
• Boiling Point: 206°Cat760mmHg
• Flash Point: 73.4°C
• PSA: 34.14000
• Density: 1.119g/cm³
• LogP: 1.03080

Purity/Quality:

95% ^*data from raw suppliers

2-Ethyl-1,4-benzoquinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Ethyl-1,4-benzoquinone are present in arthropod defense exudates and exhibit biological activity against bacteria and fungi. Defensive secretions of the European earwig Forficula auricularia against Gram-positive and Gram-negative bacteria as well as 2 entomopathogenic fungi.

Technology Process of 2-ethylcyclohexa-2,5-diene-1,4-dione

There total 21 articles about 2-ethylcyclohexa-2,5-diene-1,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

propionic acid (802294-64-0,79-09-4) + p-benzoquinone (106-51-4) → 2-ethyl-1,4-benzoquinone (4754-26-1)

Guidance literature:

With silver persulfate;

DOI:10.1021/jo026238i

Reference yield: 76.0%

ethylhydroquinone dimethyl ether (1199-08-2) → 2-ethyl-1,4-benzoquinone (4754-26-1)

Guidance literature:

With manganese(IV) oxide; nitric acid; In dichloromethane; for 1.5h; Ambient temperature;

DOI:10.1016/S0040-4039(00)61936-6

Reference yield: 75.0%

ethylhydroquinone dimethyl ether (1199-08-2) → 5,5'-diethyl-2,2'-bis-p-benzoquinone (1159550-60-3) + 2-ethyl-1,4-benzoquinone (4754-26-1)

Guidance literature:

With ammonium cerium (IV) nitrate; In water; acetonitrile; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2014.02.017

upstream raw materials:

o-Hydroxyethylbenzene

ortho-ethylaniline

2-nitro(ethylbenzene)

ethylbenzene

Refernces

• 1、 Xu, Chaoran,Zheng, Haifeng,Hu, Bowen,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming. "Chiral cobalt(II) complex catalyzed Friedel-Crafts aromatization for the synthesis of axially chiral biaryldiols". supporting information. p. 9741 - 9744. Retrieved 2017/09/07.
• 2、 Love, Brian E.,Duffy, Brian C.,Simmons, Alexander L.. "Effects of reaction conditions on quinone/diquinone product ratios in the oxidation of 1,4-dimethoxybenzene derivatives with ceric ammonium nitrate". supporting information. p. 1994 - 1997. Retrieved 2014/04/03.